专利名称：Use of dimiracetam in the treatment of
chronic pain
发明人：Carlo Farina,Carla Ghelardini,Paola Petrillo申请号：US12450944申请日：20080415公开号：US07989421B2公开日：20110802
摘要：The use of dimiracetam in the treatment of chronic pain is disclosed. At doseshigher than those previously disclosed in relation with its cognition enhancing activity (i.e.amelioration of learning and memory), dimiracetam was able to completely reverthyperalgesia or allodynia associated with several animal models of chronic pain.
Dimiracetam showed high activity in iatrogenic neuropathies associated with antiviral andchemotherapeutic drug treatments and in painful conditions caused by osteoarthritis. Inaddition, dimiracetam was devoid of toxicity even at doses 10-fold higher than the highesttherapeutic dose. The possibility of treating such debilitating pathologies with a highlyeffective and essentially non-toxic compound is therefore disclosed.
申请人：Carlo Farina,Carla Ghelardini,Paola Petrillo
地址：Milan IT,Pistoia IT,Milan IT
国籍：IT,IT,IT
代理机构：Abelman, Frayne & Schwab
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