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Data Sheet
Product Name:Cat. No.:CAS No.:
Molecular Formula:Molecular Weight:Target:Pathway:Solubility:
Mexiletine (hydrochloride)HY-A00935370-01-4C11H18ClNO215.72
Sodium Channel
Membrane Transporter/Ion ChannelDMSO: ≥ 41 mg/mL
BIOLOGICAL ACTIVITY:
Mexiletine hydrochloride is a non–selective voltage–gated sodium channel blocker; Class IB anti–arrhythmic compound.
References:
[1]. Desaphy JF, et al. Effect of mexiletine on sea anemone toxin–induced non–inactivating sodium channels of rat skeletal muscle: a model of sodiumchannel myotonia. Neuromuscul Disord. 1999 May;9(3):182–9.
[2]. Mori K, et al. Inhibitory effects of class I and IV antiarrhythmic drugs on the Na+–activated K+ channel current in guinea pig ventricular cells. NaunynSchmiedebergs Arch Pharmacol. 1998 Dec;358(6):641–8.
Caution: Product has not been fully validated for medical applications. For research use only.
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