TREATMENT OF OCULAR DISEASE

专利名称：TREATMENT OF OCULAR DISEASE发明人：Peyman, Gholam, A.申请号：EP04779223.9申请日：20040727公开号：EP1675652A2公开日：20060705

摘要：A formulation to treat ocular conditions such as dry eye disease, as well asother conditions, is disclosed. Rapamycin and/or ascomycin is administered intraocularly,such as by topical application, injection into the eye, or implantation in or on the eye. Forexample, a topical administration may contain between about 50 pg/ml drug to about 50µg/mI drug in a formulation which may be applied at bedtime or throughout the day. Forinjection, a dose of about 50 pg/ml to about 200 µg/ml may be used. Rapamycin and/orascomycin may also be administered in milligram quantities as a surgical implant, forexample, in a diffusible walled reservoir sutured to the wall of the sclera, or may becontained within an inert carrier such as microspheres or liposomes to provide a slow-release drug delivery system.

申请人：Advanced Ocular Systems Limited

地址：117 Stirling Highway Nedlands, Western Australia 6009 AU

国籍：AU

代理机构：Harding, Charles Thomas

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